Sounds like that's around #7, yeah. That's pre-Axis and the next issue(?) is post-Axis, but other than that you can pretty much follow without anny event knowledge. I have a friend who read the whole run without any knowledge of wtf was going on in the wider marvelverse.

I really really loved Al Ewing's writing of Loki, but also his writing in general. I'd say give it a go? there's some excellent stuff coming up and Verity is awesome, as always. Plus, it's not that long.